When and where this study will be done?

The study will be implemented in 14 sites in Mozambique and 14 sites in Tanzania. The sites were randomized to two arms: control and intervention arm.

Mozambique

NUMBERHEALTH FACILITYREGION OR PROVINCE
1Centro de Saúde de DONDOSofala
2Centro de Saúde de CHINGUSSURASofala
3Centro de Saúde de NHACONJOSofala
4Centro de Saúde de MUNHAVASofala
5Centro de Saúde de PONTA GEASofala
6Centro de Saúde de MANGA-LOFORTESofala
7Centro de Saúde de MAFAMBISSESofala
8Centro de Saúde de M.MASCARENHASSofala
9Centro de Saúde de MACURRUNGOSofala
10Centro de Saúde de NHAMAONHAManica
11Centro de Saúde de 1 DE MAIOManica
12Centro de Saúde de 7 DE ABRILManica
13Centro de Saúde de VILA NOVAManica
14Hospital Distrital de GONDOLAManica

Tanzania

NUMBER HEALTH FACILITY REGION OR PROVINCE
1 IGAWILO Hospital MBEYA
2 CHUNYA District Hospital MBEYA
3 TUKUYU District Hospital MBEYA
4 RUANDA Health Care Clinic MBEYA
5 CHIMALA MISSION Hospital MBEYA
6 ITETE District Hospital MBEYA
7 CHALANGWA Health Care Clinic MBEYA
8 ILEMBO Health Care Clinic MBEYA
9 UHAI Health Care Clinic MBEYA
10 IGOGWE Hospital MBEYA
11 MTANILA Health Care Clinic MBEYA
12 INYALA Health Care Clinic MBEYA
13 SONGWE REGIONAL Hospital SONGWE
14 IYULA Health Care Clinic SONGWE

Study recruitment will start in Q3/4 2019 and will continue over 2 years. The follow-up period for all mothers/infant pairs will include 12 weeks after birth, for HIV-infected infants months 6, 12, 18 after birth, and for a subset of HIV-exposed infants included into the long-term follow-up period including months 9 and 18 after birth.